Lapatinib

In the US, Lapatinib (lapatinib systemic) is a member of the following drug classes: EGFR inhibitors, HER2 inhibitors and is used to treat Breast Cancer and Breast Cancer - Metastatic.

US matches:

• Lapatinib


• Lapatinib Ditosylate

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

L01XE07

CAS registry number (Chemical Abstracts Service)

0231277-92-2

Chemical Formula

C29-H26-Cl-F-N4-O4-S

Molecular Weight

581

Therapeutic Categories

Antineoplastic agent

Tyrosine kinase inhibitor

Chemical Names

N-[3-Chlor-4-(3-fluorbenzyloxy)phenyl]-6-{5-[4-(methylsulfonyl)-2-azabutyl]-2-furyl}chinazolin-4-amin (IUPAC)

N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]quinazolin-4-amine (WHO)

4-Quinazolinamine, N-(3-chloro-4-((3-fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-

Foreign Names

• Lapatinibum (Latin)
• Lapatinib (German)
• Lapatinib (French)
• Lapatinib (Spanish)

Generic Names

• GSK 572016 (IS: GlaxoSmithKline)
• GW 572016 (IS)
• GW-2016 (IS: GlaxoSmithKline)
• Lapatinib Ditosylate (OS: USAN)
• GW572016F (IS: GlaxoSmithKline)
• Lapatinib ditosylate monohydrate (IS)

Brand Names

• Tyverb
  GlaxoSmithKline, Netherlands



• Tykerb
  GlaxoSmithKline, Australia; GlaxoSmithKline, Indonesia; GlaxoSmithKline, Japan; GlaxoSmithKline, New Zealand; GlaxoSmithKline, Oman; GlaxoSmithKline, United States



• Tyverb
  Glaxo Group, Austria; Glaxo Group, Luxembourg; Glaxo SmithKline, Spain; GlaxoSmithKline, Switzerland; GlaxoSmithKline, Germany; GlaxoSmithKline, Denmark; GlaxoSmithKline, United Kingdom; GlaxoSmithKline, Ireland; GlaxoSmithKline, Norway; GlaxoSmithKline, Sweden

International Drug Name Search

Glossary

IUPAC	International Union of Pure and Applied Chemistry
IS	Inofficial Synonym
OS	Official Synonym
Rec.INN	Recommended International Nonproprietary Name (World Health Organization)
USAN	United States Adopted Name
WHO	World Health Organization

Click for further information on drug naming conventions and International Nonproprietary Names.