Ascorbic Acid

In the US, Ascorbic acid (ascorbic acid systemic) is a member of the drug class vitamins and is used to treat Dietary Supplementation, Scurvy and Urinary Acidification.

US matches:

• Ascorbic Acid


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• Ascorbic acid and iron polysaccharide


• Ascorbic Acid Injection


• Ascorbic Acid (Vitamin C)

UK matches:

• Ascorbic Acid Tablets 500mg (Actavis UK Ltd)
• Ascorbic Acid Tablets 500mg Label Leaflet
• Ascorbic Acid Injection 500mg/5ml (UCB Pharma Ltd) (SPC)
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Ingredient matches for Ascorbic acid

Ascorbic Acid

Ascorbic acid (BAN, JAN) is known as Ascorbic Acid in the US.

International Drug Name Search

Glossary

BAN	British Approved Name
JAN	Japanese Accepted Name
SPC	Summary of Product Characteristics (UK)

Click for further information on drug naming conventions and International Nonproprietary Names.

Timoferol

Timoferol may be available in the countries listed below.

Ingredient matches for Timoferol

Ascorbic Acid

Ascorbic Acid is reported as an ingredient of Timoferol in the following countries:

• France

Ferrous Sulfate

Ferrous Sulfate is reported as an ingredient of Timoferol in the following countries:

• France

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Chlorhexamed

Chlorhexamed may be available in the countries listed below.

Ingredient matches for Chlorhexamed

Chlorhexidine

Chlorhexidine digluconate (a derivative of Chlorhexidine) is reported as an ingredient of Chlorhexamed in the following countries:

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Betoquin

Betoquin may be available in the countries listed below.

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Betaxolol

Betaxolol hydrochloride (a derivative of Betaxolol) is reported as an ingredient of Betoquin in the following countries:

• Australia

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Tramadol uno 1A-Pharma

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Tramadol

Tramadol hydrochloride (a derivative of Tramadol) is reported as an ingredient of Tramadol uno 1A-Pharma in the following countries:

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Viramid

Viramid may be available in the countries listed below.

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Ribavirin

Ribavirin is reported as an ingredient of Viramid in the following countries:

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Fenticol

Fenticol may be available in the countries listed below.

In some countries, this medicine may only be approved for veterinary use.

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Thiamphenicol

Thiamphenicol is reported as an ingredient of Fenticol in the following countries:

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Anreb

Anreb may be available in the countries listed below.

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Losartan

Losartan potassium salt (a derivative of Losartan) is reported as an ingredient of Anreb in the following countries:

• Bangladesh

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GlucaGen Novo Nordisk

GlucaGen Novo Nordisk may be available in the countries listed below.

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Glucagon

Glucagon hydrochloride (a derivative of Glucagon) is reported as an ingredient of GlucaGen Novo Nordisk in the following countries:

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Topocid

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Fusidic Acid

Fusidic Acid is reported as an ingredient of Topocid in the following countries:

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Dinoprostone

Class: Oxytocics
ATC Class: G02AD02
VA Class: HS875
Chemical Name: (5Z, 11a, 13E, 15S)-11,15-Dihydroxy-9-oxo-prosta-5,13-dien-1-oic acid
Molecular Formula: C₂₀H₃₂O₅
CAS Number: 363-24-6
Brands: Cervidil, Prepidil, Prostin E2

Introduction

Stimulates uterine smooth muscle and also produces cervical dilation and softening; prostaglandin E₂.^{a 200 213 214}

Uses for Dinoprostone

Termination of Pregnancy

Termination of intrauterine pregnancy during the second trimester (12–20th week of gestation, dated from the first day of the last menstrual period).^{a e 200}

For termination of pregnancy, has been used in conjunction with oxytocin to reduce the dinoprostone dose and number of adverse effects associated with dinoprostone.^{a e f}

Evacuation of uterine contents in cases of missed abortion, intrauterine fetal death up to 28 weeks of gestational age, or nonmetastatic gestational trophoblastic disease (benign hydatidiform mole).^{a e 200}

Labor Induction (Cervical “Ripening”)

Treatment to improve cervical inducibility (cervical “ripening”) in pregnant women at or near term with a medical or obstetrical need for labor induction.^{212 213 216 217 218 219 220 h}

Postpartum Hemorrhage

Has been used in the management of postpartum hemorrhage†.^g

Dinoprostone Dosage and Administration

Administration

Vaginal Administration

Administer intravaginally as a vaginal suppository (Prostin E2), cervical gel (Prepidil), or vaginal insert (Cervidil).^{200 212 213}

Vaginal Suppositories

Allow suppository to reach room temperature just prior to administration.²⁰⁰

Remove the foil wrapper and insert the suppository high into the posterior vaginal fornix.^{200 a} Patient should remain supine for 10 minutes following each insertion.²⁰⁰ May require the use of a diaphragm to prevent displacement of the suppository from the paracervical area.^a

Cervical Gel

Allow the gel to reach room temperature just prior to administration; do not use a water bath or other source of external heat (e.g., microwave oven) to facilitate the warming process.²¹²

Consult the manufacturer’s instructions for proper assembly of the syringe and catheter.²¹²

Administer the cervical gel (supplied in a syringe) through a shielded catheter into the cervical canal.²¹² Select the proper size catheter based on the degree of effacement; if no effacement is present, use the 20-mm catheter; for 50% effacement, use the 10-mm catheter.²¹²

Place patient in a dorsal position and visualize the cervix using a speculum.²¹² Using sterile technique, introduce the gel via the catheter into the cervical canal, just below the level of the internal os.²¹² Remove the catheter.²¹² Patient should remain supine for at least 15–30 minutes to minimize leakage from the cervical canal.²¹²

Vaginal Insert

Keep frozen until use.^d

After removal from the protective package (tear at designated mark),^d place the vaginal insert transversely in the posterior fornix of the vagina.²¹³ May use a small amount of water-soluble lubricant to assist insertion; excess contact or coating with lubricant may prevent optimal swelling and release of dinoprostone from the insert.²¹³ Patient should remain supine for 2 hours following insertion.²¹³ If patient is ambulatory, ensure that the vaginal insert remains in place.^d

Use the knitted polyester retrieval system to aid in drug retrieval at the end of the dosing interval.²¹³ Upon removal of the insert, ensure that the slab is removed.^d If the slab is not found in the retrieval system, perform a vaginal examination to remove the slab.^d

Formulation Considerations

Dinoprostone vaginal suppositories and any preparation made extemporaneously from dinoprostone vaginal suppositories should not be used at term for cervical “ripening”;²⁰⁰ dinoprostone cervical gel and vaginal insert are used at or near term to improve cervical inducibility.^{212 213}

Dinoprostone vaginal suppositories should not be used for extemporaneous preparation of any other dosage form.²⁰⁰

Dosage

Adults

Termination of Pregnancy

Intravaginal

Vaginal suppositories: 20 mg every 3–5 hours until abortion occurs; adjust the dosing intervals according to abortifacient progress, uterine contractility, and patient tolerance.^{a 200}

Vaginal suppositories: Initial dose of 5 mg, repeated as needed, when used for intrauterine fetal death at >24 weeks’ gestational age.^e (See Prescribing Limits.)

Induction of Labor (Cervical “Ripening”)

Intravaginal

Cervical gel: Initially, 0.5 mg (2.5 mL of gel).²¹² If there is no cervical and/or uterine response to the initial dose, administer another 0.5-mg dose after 6–12 hours.^{212 220} Clinician should determine the need for additional doses and the dosing intervals.²¹²

Vaginal insert: 1 insert delivering dinoprostone 0.3 mg/hour for 12 hours.²¹³ Remove after 12 hours, at the onset of active labor, or if uterine hyperstimulation develops.^{213 d}

Postpartum Hemorrhage†

Intravaginal or Rectal

Vaginal suppositories: 20 mg every 2 hours has been used.^g

Prescribing Limits

Adults

Termination of Pregnancy

Intravaginal Vaginal suppositories

Intravaginal Vaginal suppositories: Use for >2 days not recommended.²⁰⁰

Vaginal suppositories: Initially 5 mg; repeat as needed when used for intrauterine fetal death at >24 weeks, gestational age.^e Use of 20-mg dose may result in uterine rupture.^e

Intravaginal

Cervical gel: Maximum cumulative dose is 1.5 mg (7.5 mL)/24 hours.^{212 220}

Cautions for Dinoprostone

Contraindications

• 
  

  Known hypersensitivity to prostaglandins or any ingredient in the formulation.^{200 212 213}

  
  


• 
  

  Dinoprostone vaginal suppositories are contraindicated in patients with acute pelvic inflammatory disease and in those with active cardiac, pulmonary, renal, or hepatic disease.²⁰⁰

  
  


• 
  

  Dinoprostone cervical gel and vaginal inserts are contraindicated in patients with contraindications to oxytocic agents and when prolonged contractions of the uterus are inappropriate (e.g., previous cesarean section, previous major uterine surgery, history of difficult labor and/or traumatic delivery, marked cephalopelvic disproportion, unfavorable fetal position, ≥6 previous term pregnancies, fetal distress when delivery is not imminent, hyperactive or hypertonic uterus, obstetric emergencies where maternal or fetal risk-to-benefit ratio favors surgery).^{212 213}

  
  


• 
  

  Dinoprostone cervical gel and vaginal inserts are contraindicated in patients with placenta previa or unexplained vaginal bleeding during the current pregnancy.^{212 213}

  
  


• 
  

  Dinoprostone cervical gel is contraindicated when vaginal delivery is not indicated (e.g., vasa previa, active genital herpes infection).²¹²

  
  


• 
  

  The manufacturer of dinoprostone vaginal inserts states that this preparation is contraindicated in patients receiving IV oxytocic therapy.²¹³

  
  

Warnings/Precautions

Warnings

Administer by qualified professional personnel in a hospital where intensive care and surgical facilities are immediately available.^{a 200 212}

Considerations in Patients Undergoing Termination of Pregnancy

Dinoprostone does not affect the fetoplacental unit.²⁰⁰ Possibility exists that a previable fetus could exhibit transient signs of life following dinoprostone-induced abortion; dinoprostone is not indicated if the fetus has reached the stage of viability.²⁰⁰ If pregnancy is terminated because of late fetal intrauterine death, confirm fetal death prior to administration of dinoprostone.²⁰⁰

If the pregnancy is not terminated with dinoprostone, complete abortion by another method.²⁰⁰

Confirm pregnancy termination for pregnancy diagnosed as missed abortion.²⁰⁰

Considerations in Patients Undergoing Induction of Labor (Cervical “Ripening”)

Monitor uterine contractions, fetal status (e.g., heart rate), and progression of cervical dilation and effacement of the cervix to avoid complications.^{220 212 213}

Use with caution in patients with ruptured membranes.^{c d}

Carefully select patients; evaluate both maternal and fetal condition before dinoprostone use.^{212 213 220} (See Contraindications.)

Consider removing dinoprostone vaginal insert if sustained uterine contractions, fetal distress, or other fetal or maternal adverse effects occur.²¹³ Remove the insert if uterine hyperstimulation develops or labor starts.²¹³ Remove the insert before amniotomy.²¹³

General Precautions

Musculoskeletal Effects

Proliferation of long bones reported in neonates receiving long-term therapy with alprostadil (prostaglandin E₁).^{200 a i} No evidence that short-term administration of dinoprostone has similar effects on bone.^{200 a}

Concomitant Diseases

Caution in patients with cervicitis, infected endocervical lesions, acute vaginitis, compromised (scarred) uterus, asthma or a history of asthma, hypertension or hypotension, seizure disorders, diabetes mellitus, glaucoma, increased IOP, anemia, jaundice, or cardiovascular, renal, or hepatic disease.^{200 212 213 a b}

Fever

Transient fever (i.e., temperature elevations >1.1°C) reported.²⁰⁰ When used for termination of pregnancy, may be difficult to distinguish drug-induced temperature elevations from post-abortion endometritis.²⁰⁰

Specific Populations

Pregnancy

Category C.^{200 212 213}

Pediatric Use

Safety and efficacy not established in children.^{200 212 213} Safety and efficacy in adolescents expected to be the same as in adults.²¹³

Hepatic Impairment

Use with caution.^{200 212}

Dinoprostone vaginal suppositories are contraindicated in patients with active hepatic disease.²⁰⁰

Renal Impairment

Use with caution.^{200 212}

Dinoprostone vaginal suppositories are contraindicated in patients with active renal disease.²⁰⁰

Common Adverse Effects

Dinoprostone vaginal suppositories: Vomiting, transient fever, diarrhea, nausea, headache, chills, transient DBP decreases of >20 mm Hg.²⁰⁰

Dinoprostone cervical gel or vaginal insert: Uterine hyperstimulation, fetal heart rate abnormality, adverse GI effects, back pain, fever.^{212 213}

Interactions for Dinoprostone

Specific Drugs

Drug	Interaction	Comments
Oxytocic agents (e.g., oxytocin)	May increase activity of other oxytocic agents200 212 213	Concomitant use not recommended200 212 213 Dinoprostone cervical gel: Allow an inteval of 6–12 hours between administration of the cervical gel and initiation of IV oxytocin212 220 Dinoprostone vaginal insert: Wait ≥30 minutes between removal of dinoprostone vaginal insert and initiation of IV oxytocin213 220

Dinoprostone Pharmacokinetics

Absorption

Bioavailability

Absorbed systemically following vaginal administration as dinoprostone suppositories; a small amount of drug is absorbed directly by the uterus through the cervix or local lymphatic or vascular channels.^a

Dinoprostone cervical gel: Peak plasma concentrations achieved in 30–45 minutes.²¹²

Dinoprostone vaginal insert: A controlled-release preparation designed to release 0.3 mg of dinoprostone per hour for 12 hours.²¹³

Onset

Dinoprostone vaginal suppositories: Slight uterine contractions begin within 10 minutes (first and second trimester pregnancies).^a

Duration

Dinoprostone vaginal suppositories: Contractions continue for 2–3 hours (first and second trimester pregnancies).^a

Distribution

Extent

Widely distributed in the mother.^a

Elimination

Metabolism

Rapidly metabolized in the maternal lungs, kidneys, spleen, and other tissues, primarily by oxidation of the side chains to at least 9 inactive metabolites.^a

Elimination Route

Drug and its metabolites excreted principally in urine; small amounts excreted in feces.^a

Half-life

2.5–5 minutes.²¹³

Stability

Storage

Vaginal

Gel

2–8°C.²¹²

Insert

-20°C to -10°C.²¹³ Protect from moisture and humidity.²¹³

Suppositories

Do not exceed -20°C.²⁰⁰

ActionsActions

• 
  

  Elicits pharmacologic responses usually produced by endogenous prostaglandin E₂.^{200 212 213}

  
  


• 
  

  Increases the amplitude and frequency of uterine contractions throughout pregnancy; uterine response to the drug increases with the duration of pregnancy.^a

  
  


• 
  

  Produces local cervical effects including softening, effacement, and dilation.^{212 213 214}

  
  


• 
  

  Causes stimulation of the circular smooth muscle of the GI tract, increasing GI motility. ^a

  
  

Advice to Patients

• 
  

  Importance of informing clinicians of existing or contemplated concomitant therapy, including prescription and OTC drugs, as well as any concomitant illnesses.^{200 212 213}

  
  


• 
  

  Importance of informing patients of other important precautionary information.^{200 212 213} (See Cautions.)

  
  

Preparations

Excipients in commercially available drug preparations may have clinically important effects in some individuals; consult specific product labeling for details.

Dinoprostone

Routes	Dosage Forms	Strengths	Brand Names	Manufacturer
Vaginal	Gel	0.5 mg/3 g	Prepidil	Pfizer
	Insert	10 mg	Cervidil	Forest
	Suppositories	20 mg	Prostin E2	Pfizer

Disclaimer

This report on medications is for your information only, and is not considered individual patient advice. Because of the changing nature of drug information, please consult your physician or pharmacist about specific clinical use.

The American Society of Health-System Pharmacists, Inc. and Drugs.com represent that the information provided hereunder was formulated with a reasonable standard of care, and in conformity with professional standards in the field. The American Society of Health-System Pharmacists, Inc. and Drugs.com make no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, with respect to such information and specifically disclaims all such warranties. Users are advised that decisions regarding drug therapy are complex medical decisions requiring the independent, informed decision of an appropriate health care professional, and the information is provided for informational purposes only. The entire monograph for a drug should be reviewed for a thorough understanding of the drug's actions, uses and side effects. The American Society of Health-System Pharmacists, Inc. and Drugs.com do not endorse or recommend the use of any drug. The information is not a substitute for medical care.

AHFS Drug Information. © Copyright, 1959-2011, Selected Revisions January 2008. American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland 20814.

† Use is not currently included in the labeling approved by the US Food and Drug Administration.

References

200. Pharmacia & Upjohn Company. Prostin E2 (dinoprostone vaginal suppository) prescribing information (dated 1999 Aug). In: Physician’s desk reference. 55th ed. Montvale, NJ: Medical Economics Company Inc; 2001:2638-9.

201. Rayburn W, Gosen R, Ramadei C et al. Outpatient cervical ripening with prostaglandin E₂ gel in uncomplicated postdate pregnancies. Am J Obstet Gynecol. 1988; 158:1417-23. [IDIS 310426] [PubMed 3289398]

202. Nager CW, Key TC, Moore TR. Cervical ripening and labor outcome with preinduction intracervical prostaglandin E2 (Prepidil) gel. J Perinatol. 1987; 7:189-93. [PubMed 3504454]

203. Trofatter KF Jr, Bowers D, Gall SA et al. Preinduction cervical ripening with prostaglandin E₂ (Prepidil) gel. Am J Obstet Gynecol. 1985; 153:268-71. [IDIS 207501] [PubMed 3901764]

204. Neilson DR Jr, Prins RP, Bolton RN et al. A comparison of prostaglandin E₂ gel and prostaglandin F_2α gel for preinduction cervical ripening. Am J Obstet Gynecol. 1983; 146:526-32. [IDIS 172356] [PubMed 6344644]

205. Lorenz RP, Botti JJ, Chez RA et al. Variations of biologic activity of low-dose prostaglandin E₂ on cervical ripening. Obstet Gynecol. 1984; 64:123-7. [IDIS 187151] [PubMed 6377145]

206. Prins RP, Bolton RN, Mark C III et al. Cervical ripening with intravaginal prostaglandin E2 gel. Obstet Gynecol. 1983; 61:459-62. [IDIS 168236] [PubMed 6572335]

207. Ulmsten U, Wingerup L, Andersson KE. Comparison of prostaglandin E₂ and intravenous oxytocin for induction of labor. Obstet Gynecol. 1979; 54:581-4. [IDIS 107185] [PubMed 503385]

208. Dingfelder JR, Brenner WE, Hendricks CH et al. Reduction of cervical resistance by prostaglandin suppositories prior to dilatation for induced abortion. Am J Obstet Gynecol. 1975; 122:25-30. [PubMed 1130444]

209. Jagani N, Schulman H, Fleischer A et al. Role of prostaglandin-induced cervical changes in labor induction. Obstet Gynecol. 1984; 63:225-9. [IDIS 181001] [PubMed 6582419]

210. Buchanan D, Macer J, Yonekura ML. Cervical ripening with prostaglandin E₂ vaginal suppositories. Obstet Gynecol. 1984; 63:659-63. [IDIS 184594] [PubMed 6585733]

211. Lagrew DC, Freeman RK. Management of postdate pregnancy. Am J Obstet Gynecol. 1986; 154:8-13. [PubMed 3946506]

212. Pharmacia & Upjohn Company. Prepidil Gel (dinoprostone cervical gel) prescribing information (dated 1999 Apr). In: Physician’s desk reference. 55th ed. Montvale, NJ: Medical Economics Company Inc; 2001:2637-8.

213. Forest Pharmaceuticals. Cervidil (dinoprostone vaginal insert) prescribing information (dated 2000 Feb). In: Physician’s desk reference. 55th ed. Montvale, NJ: Medical Economics Company Inc; 2001:1261-3.

214. Bryman I, Norstrom A, Lindblom B. Has cervical smooth muscle any physiological role in the human? Acta Physiol Hung. 1985; 65:327-30.

215. MacLennan AH, Katz M, Creasy R. The morphologic characteristics of cervical ripening induced by the hormones relaxin and prostaglandin F₂ alpha in a rabbit model. Am J Obstet Gynecol. 1985; 152(6 pt 1):691-6. [PubMed 3861093]

216. Sadaty A, Pagano M, Greer C et al. A randomized trial of vaginal prostaglandin E(2) gel and dinoprostone vaginal insert for induction of labor at term. Prim Care Update Ob Gyns. 1998; 5:183. [PubMed 10838343]

217. Warke HS, Saraogi RM, Sanjwalla SM. Prostaglandin E2 gel In ripening of cervix in induction of labour. J Postgrad Med. 1999; 45:105-9. [PubMed 10734347]

218. Wieland D, Friedman F Jr. Comparing two dinoprostone agents for preinduction cervical ripening at term: a randomized trial. J Reprod Med. 1999; 44:724-8. [IDIS 435924] [PubMed 10483544]

219. McKenna DS, Costa SW, Samuels P. Prostaglandin E2 cervical ripening without subsequent induction of labor. Obstet Gynecol. 1999; 94:11-4. [IDIS 430673] [PubMed 10389710]

220. American College of Obstetricians and Gynecologists (ACOG) Committee on Practice Bulletins. Induction of labor. Practice Bulletin No. 10. Washington, DC: American College of Obstetricians and Gynecologists; 1999 Nov.

a. AHFS Drug Information 2007. McEvoy GK, ed. Dinoprostone. Bethesda, MD: American Society of Health-System Pharmacists; 2007: 3267-9.

b. Pharmacia and UpJohn. Prostin E2 (dinoprostone) vaginal suppository prescribing information. New York, NY; 2006 Apr..

c. Pharmacia and UpJohn . Prepidil (dinoprostone) cervical gel prescribing information. New York, NY; 2006 Nov.

d. Forest Pharmaceuticals, Inc. Cervidil (dinoprostone) vaginal insert prescribing information. St Louis, MO; 2006 May.

e. Stubblefield PG, Carr-Ellis S, Borgatta L. Methods for induced abortion. Obstet Gynecol. 2004; 104:174-85. [PubMed 15229018]

f. Ramsey PS, Savage K, Lincoln T, Owen J. Vaginal misoprostol versus concentrated oxytocin and vaginal PGE₂ for second-trimester labor induction. Obstet Gynecol. 2004; 104:138-45. [PubMed 15229013]

g. American College of Obstetricians and Gynecologists (ACOG) Committee Practice Bulletin. Postpartum hemorrhage. Practice Bulletin No. 76. Washington, DC: American College of Obstetricians and Gynecologists; 2006 Oct.

h. Briggs GG, Wan SR. Drug therapy during labor and delivery, part 2. Am J Health-Syst Pharm. 2006; 63:1131-9. [PubMed 16754739]

i. Pharmacia. Prostin VR Pediatric (alprostadil) injection prescribing information. Kalamazoo, MI; 2002 Aug.

More Dinoprostone resources

• Dinoprostone Side Effects (in more detail)
• Dinoprostone Use in Pregnancy & Breastfeeding
• Dinoprostone Drug Interactions
• Dinoprostone Support Group
• 2 Reviews for Dinoprostone - Add your own review/rating

Compare Dinoprostone with other medications

• Abortion
• Labor Induction
• Trophoblastic Disease

Re-Tann

Generic Name: carbetapentane and pseudoephedrine (kar BAY ta PEN tane and SOO doe ee FED rin)

Brand Names: Allres Pd, Carb Pseudo-Tan, Corzall, Pseudacarb, Re-Tann, Respi-TANN, Respi-Tann Pd

What is Re-Tann (carbetapentane and pseudoephedrine)?

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Carbetapentane is a cough suppressant. It affects the signals in the brain that trigger cough reflex.

The combination of carbetapentane and pseudoephedrine is used to treat cough and nasal and sinus congestion caused by the common cold, flu, or bronchitis.

Carbetapentane and pseudoephedrine may also be used for purposes not listed in this medication guide.

What is the most important information I should know about Re-Tann (carbetapentane and pseudoephedrine)?

Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Ask a doctor or pharmacist before using any cough, cold, or allergy medicine. Many combination medicines available over the counter may contain similar drug ingredients. Taking certain products together can cause you to get too much of a certain drug. Check the label to see if a medicine contains a decongestant or cough suppressant. Do not take a cough or cold medicine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

What should I discuss with my healthcare provider before taking Re-Tann (carbetapentane and pseudoephedrine)?

Do not take a cough or cold medicine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects. You should not take this medication if you are allergic to carbetapentane or pseudoephedrine, or if you have severe or untreated high blood pressure or coronary artery disease.

To make sure you can safely take carbetapentane and pseudoephedrine, tell your doctor if you have any of these other conditions:

• 
  

  heart disease or high blood pressure;

  
  


• 
  

  a seizure disorder;

  
  


• 
  

  glaucoma;

  
  


• 
  

  an enlarged prostate or problems with urination;

  
  


• 
  

  diabetes; or

  
  


• 
  

  a thyroid disorder.

  
  

FDA pregnancy category C. It is not known whether carbetapentane and pseudoephedrine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Carbetapentane and pseudoephedrine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take Re-Tann (carbetapentane and pseudoephedrine)?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Do not give this medication to a child younger than 2 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

Measure liquid medicine with a special dose-measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

The chewable tablet must be chewed before you swallow it.

Do not take carbetapentane and pseudoephedrine for longer than 7 days in a row. Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

If you need surgery, tell the surgeon ahead of time if you have taken a cough or cold medicine within the past few days.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Since cough or cold medicine is taken when needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Re-Tann (carbetapentane and pseudoephedrine)?

This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Drinking alcohol can increase certain side effects of carbetapentane and pseudoephedrine.

Avoid taking this medication if you also take diet pills, caffeine pills, or other stimulants (such as ADHD medications). Taking a stimulant together with a decongestant can increase your risk of unpleasant side effects.

Ask a doctor or pharmacist before using any cough, cold, or allergy medicine. Many combination medicines available over the counter may contain similar drug ingredients. Taking certain products together can cause you to get too much of a certain drug. Check the label to see if a medicine contains a decongestant or cough suppressant.

Re-Tann (carbetapentane and pseudoephedrine) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop taking this medication and call your doctor at once if you have a serious side effect such as:

• 
  

  fast, pounding, or uneven heartbeat;

  
  


• 
  

  severe dizziness, anxiety, restless feeling, or nervousness;

  
  


• 
  

  confusion, hallucinations;

  
  


• 
  

  slow, shallow breathing;

  
  


• 
  

  easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms; or

  
  


• 
  

  dangerously high blood pressure (severe headache, blurred vision, ringing in your ears, anxiety, confusion, chest pain, trouble breathing, uneven heart rate, seizure).

  
  

Less serious side effects may include:

• 
  

  loss of appetite, upset stomach;

  
  


• 
  

  warmth, redness, or tingling under your skin;

  
  


• 
  

  feeling excited or restless;

  
  


• 
  

  sleep problems (insomnia); or

  
  


• 
  

  mild skin rash or itching.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Re-Tann (carbetapentane and pseudoephedrine)?

Tell your doctor about all other medicines you use, especially:

• 
  

  celecoxib (Celebrex);

  
  


• 
  

  cinacalcet (Sensipar);

  
  


• 
  

  darifenacin (Enablex);

  
  


• 
  

  imatinib (Gleevec);

  
  


• 
  

  quinidine (Quin-G);

  
  


• 
  

  ranolazine (Ranexa)

  
  


• 
  

  ritonavir (Norvir, Kaletra);

  
  


• 
  

  sibutramine (Meridia);

  
  


• 
  

  terbinafine (Lamisil);

  
  


• 
  

  medicines to treat high blood pressure;

  
  


• 
  

  an antidepressant such as amitriptyline (Elavil, Vanatrip), bupropion (Wellbutrin, Zyban), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), imipramine (Janimine, Tofranil), paroxetine (Paxil), sertraline (Zoloft), and others; or

  
  


• 
  

  a beta-blocker such as atenolol (Tenormin, Tenoretic), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others.

  
  

This list is not complete and other drugs may interact with carbetapentane and pseudoephedrine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Re-Tann resources

• Re-Tann Side Effects (in more detail)
• Re-Tann Use in Pregnancy & Breastfeeding
• Re-Tann Drug Interactions
• Re-Tann Support Group
• 0 Reviews for Re-Tann - Add your own review/rating

• Corzall Liquid MedFacts Consumer Leaflet (Wolters Kluwer)


• Corzall Prescribing Information (FDA)


• Respi-Tann Chewable Tablets MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Re-Tann with other medications

• Cough and Nasal Congestion

Where can I get more information?

• Your pharmacist can provide more information about carbetapentane and pseudoephedrine.

See also: Re-Tann side effects (in more detail)

Tibéral

Tibéral may be available in the countries listed below.

Ingredient matches for Tibéral

Ornidazole

Ornidazole is reported as an ingredient of Tibéral in the following countries:

• France

International Drug Name Search

Inhitril

Inhitril may be available in the countries listed below.

Ingredient matches for Inhitril

Trandolapril

Trandolapril is reported as an ingredient of Inhitril in the following countries:

• Indonesia

International Drug Name Search

Nistatina Denver

Nistatina Denver may be available in the countries listed below.

Ingredient matches for Nistatina Denver

Nystatin

Nystatin is reported as an ingredient of Nistatina Denver in the following countries:

• Argentina

International Drug Name Search

Decdan

Decdan may be available in the countries listed below.

Ingredient matches for Decdan

Dexamethasone

Dexamethasone is reported as an ingredient of Decdan in the following countries:

• India

Dexamethasone 21-(disodium phosphate) (a derivative of Dexamethasone) is reported as an ingredient of Decdan in the following countries:

• India

International Drug Name Search

Afinitor

In the US, Afinitor (everolimus systemic) is a member of the following drug classes: mTOR inhibitors, selective immunosuppressants and is used to treat Brain Tumor, Pancreatic Cancer and Renal Cell Carcinoma.

US matches:

• Afinitor

Ingredient matches for Afinitor

Everolimus

Everolimus is reported as an ingredient of Afinitor in the following countries:

• Australia


• Finland


• France


• Germany


• Greece


• Sweden


• Switzerland


• United Kingdom


• United States

International Drug Name Search

Trimethotab

Trimethotab may be available in the countries listed below.

In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Trimethotab

Sulfadiazine

Sulfadiazine is reported as an ingredient of Trimethotab in the following countries:

• Australia

Trimethoprim

Trimethoprim is reported as an ingredient of Trimethotab in the following countries:

• Australia

International Drug Name Search

Aspégic Enfants

Aspégic Enfants may be available in the countries listed below.

Ingredient matches for Aspégic Enfants

Aspirin

Acetylsalicylic Acid lysine (a derivative of Acetylsalicylic Acid) is reported as an ingredient of Aspégic Enfants in the following countries:

• France

International Drug Name Search

Maxef

Maxef may be available in the countries listed below.

Ingredient matches for Maxef

Cefepime

Cefepime Hydrochloride (a derivative of Cefepime) is reported as an ingredient of Maxef in the following countries:

• Mexico

International Drug Name Search

Cardioquin

In the US, Cardioquin (quinidine systemic) is a member of the drug class group I antiarrhythmics and is used to treat Arrhythmia and Malaria.

US matches:

• Cardioquin

Ingredient matches for Cardioquin

Quinidine

Quinidine polygalacturonate (a derivative of Quinidine) is reported as an ingredient of Cardioquin in the following countries:

• United States

International Drug Name Search

Metamizol Cinfamed

Metamizol Cinfamed may be available in the countries listed below.

Ingredient matches for Metamizol Cinfamed

Metamizole

Metamizole magnesium (a derivative of Metamizole) is reported as an ingredient of Metamizol Cinfamed in the following countries:

• Spain

International Drug Name Search

Primidon Era

Primidon Era may be available in the countries listed below.

Ingredient matches for Primidon Era

Primidone

Primidone is reported as an ingredient of Primidon Era in the following countries:

• Denmark

International Drug Name Search

Tasmar

In the US, Tasmar (tolcapone systemic) is a member of the drug class dopaminergic antiparkinsonism agents and is used to treat Parkinson's Disease.

US matches:

• Tasmar

UK matches:

• Tasmar 100 mg Tablets
• Tasmar 100 mg Tablets (Meda Pharmaceuticals ) (SPC)

Ingredient matches for Tasmar

Tolcapone

Tolcapone is reported as an ingredient of Tasmar in the following countries:

• Argentina


• Austria


• Belgium


• Brazil


• Chile


• Costa Rica


• Czech Republic


• Denmark


• Finland


• France


• Germany


• Ireland


• Italy


• Luxembourg


• Mexico


• Netherlands


• New Zealand


• Peru


• Philippines


• Russian Federation


• Singapore


• Slovakia


• Slovenia


• South Africa


• Spain


• Sweden


• Switzerland


• United Kingdom


• United States

International Drug Name Search

Glossary

SPC	Summary of Product Characteristics (UK)

Click for further information on drug naming conventions and International Nonproprietary Names.

Alprazolam Stada

Alprazolam Stada may be available in the countries listed below.

Ingredient matches for Alprazolam Stada

Alprazolam

Alprazolam is reported as an ingredient of Alprazolam Stada in the following countries:

• Spain


• Sweden

International Drug Name Search

Candiplas

Candiplas may be available in the countries listed below.

Ingredient matches for Candiplas

Miconazole

Miconazole nitrate (a derivative of Miconazole) is reported as an ingredient of Candiplas in the following countries:

• Bahrain


• Oman


• Sri Lanka


• Taiwan

International Drug Name Search

Filostin

Filostin may be available in the countries listed below.

In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Filostin

Colistin Sulfate

Colistin sulfate (a derivative of Colistin) is reported as an ingredient of Filostin in the following countries:

• Italy

International Drug Name Search

Pirofen

Pirofen may be available in the countries listed below.

Ingredient matches for Pirofen

Paracetamol

Paracetamol is reported as an ingredient of Pirofen in the following countries:

• Turkey

International Drug Name Search

Streptipenprokain

Streptipenprokain may be available in the countries listed below.

In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Streptipenprokain

Benzylpenicillin

Benzylpenicillin procaine (a derivative of Benzylpenicillin) is reported as an ingredient of Streptipenprokain in the following countries:

• Norway

Dihydrostreptomycin

Dihydrostreptomycin sulfate (a derivative of Dihydrostreptomycin) is reported as an ingredient of Streptipenprokain in the following countries:

• Norway

International Drug Name Search

Readi-Cat 2 oral and rectal

Generic Name: barium sulfate (oral and rectal) (BER ee um SUL fate)

Brand Names: Anatrast, Bar-Test, Baricon, Baro-Cat, Barosperse, Bear-E-Yum GI, CheeTah, CheeTah Butterscotch, CheeTah Chocolaty-Fudge, CheeTah Orange, CheeTah Raspberry, Digibar 190, E-Z AC, E-Z Disk, E-Z Dose Kit with Polibar Plus, E-Z Paste, E-Z-Cat, E-Z-Cat Dry, E-Z-HD, E-Z-Paque, Enecat, Eneset 2, Enhancer, Entero VU, Entero-H, Entrobar, Esopho-Cat, Intropaste, Liqui-Coat HD, Liquid Barosperse, Liquid E-Z Paque, Liquid Polibar, Liquid Polibar Plus, Maxibar, Medebar Plus, Medebar Super 250, Polibar ACB, Readi-Cat, Readi-Cat 2, Scan C, Sitzmarks, Smoothie Readi-Cat 2, Sol-O-Pake, Tagitol V, Tonojug, Tonopaque, Varibar Honey, Varibar Nectar, Varibar Pudding, Varibar Thin, Varibar Thin Honey, Volumen

What is barium sulfate?

Barium sulfate is in a group of drugs called contrast agents. Barium sulfate works by coating the inside of your esophagus, stomach, or intestines which allows them to be seen more clearly on a CT scan or other radiologic (x-ray) examination.

Barium sulfate is used to help diagnose certain disorders of the esophagus, stomach, or intestines.

Barium sulfate may also be used for purposes not listed in this medication guide.

What is the most important information I should know about barium sulfate?

You should not use this medication if you are allergic to barium sulfate. Tell your doctor if you have ever had an allergic reaction to a contrast agent.

Before you use barium sulfate, tell your doctor if you have any allergies, or if you have asthma, cystic fibrosis, heart disease or high blood pressure, rectal cancer, a colostomy, a blockage in your stomach or intestines, a condition called pseudotumor cerebri, or if you have recently had a rectal biopsy or surgery on your esophagus, stomach, or intestines.

Tell your doctor if you are pregnant or breast-feeding before your medical test.

Carefully follow your doctor's instructions about what to eat or drink within the 24-hour period before your test.

Serious side effects of barium sulfate may include severe stomach pain, sweating, ringing in your ears, pale skin, weakness, or severe cramping, diarrhea, or constipation

What should I discuss with my health care provider before using barium sulfate?

You should not use barium sulfate if you are allergic to it. Tell your doctor if you have ever had an allergic reaction to a contrast agent.

To make sure you can safely use barium sulfate, tell your doctor if you have any of these other conditions:

• 
  

  asthma, eczema, or allergies;

  
  


• 
  

  a blockage in your stomach or intestines;

  
  


• 
  

  cystic fibrosis;

  
  


• 
  

  a colostomy;

  
  


• 
  

  rectal cancer;

  
  


• 
  

  heart disease or high blood pressure;

  
  


• 
  

  Hirschsprung's disease (a disorder of the intestines);

  
  


• 
  

  a condition called pseudotumor cerebri (high pressure inside the skull that may cause headaches, vision loss, or other symptoms);

  
  


• 
  

  a recent history of surgery on your esophagus, stomach, or intestines;

  
  


• 
  

  a history of perforation (a hole or tear) in your esophagus, stomach, or intestines;

  
  


• 
  

  if you have recently had a rectal biopsy;

  
  


• 
  

  if you have ever choked on food by accidentally inhaling it into your lungs;

  
  


• 
  

  if you are allergic to simethicone (Gas-X, Phazyme, and others); or

  
  


• 
  

  if you are allergic to latex rubber.

  
  

It is not known whether barium sulfate will harm an unborn baby, but the radiation used in x-rays and CT scans may be harmful. Before your medical test, tell your doctor if you are pregnant. Barium sulfate may pass into breast milk and could harm a nursing baby. Before your medical test, tell your doctor if you are breast-feeding a baby.

How should I use barium sulfate?

Use this medication exactly as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended.

Barium sulfate comes in tablets, paste, cream, or liquid forms.

In some cases, barium sulfate is taken by mouth. The liquid form may also be used as a rectal enema.

You may need to begin using this medication at home a day before your medical test. Follow your doctor's instructions about how much of the medication to use and how often.

If you are receiving barium sulfate as a rectal enema, a healthcare professional will give you the medication at the clinic or hospital where your testing will take place.

Do not crush, chew, or break a barium sulfate tablet. Swallow the pill whole.

Dissolve the barium sulfate powder in a small amount of water. Stir this mixture and drink all of it right away. To make sure you get the entire dose, add a little more water to the same glass, swirl gently and drink right away.

If you receive the medication as a liquid to take by mouth, shake the liquid well just before you measure a dose. To be sure you get the correct dose, measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Carefully follow your doctor's instructions about what to eat or drink within the 24-hour period before your test.

Store at room temperature away from heat and moisture. Keep the bottle tightly closed when not in use.

What happens if I miss a dose?

If you are using barium sulfate at home, call your doctor for instructions if you miss a dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include severe stomach pain, ongoing diarrhea, confusion, or weakness.

What should I avoid before or after using barium sulfate?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Barium sulfate side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:

• 
  

  severe stomach pain;

  
  


• 
  

  severe cramping, diarrhea, or constipation;

  
  


• 
  

  sweating;

  
  


• 
  

  ringing in your ears;

  
  


• 
  

  confusion, fast heart rate; or

  
  


• 
  

  pale skin, weakness.

  
  

Less serious side effects may include:

• 
  

  mild stomach cramps;

  
  


• 
  

  nausea, vomiting;

  
  


• 
  

  loose stools or mild constipation.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect barium sulfate?

There may be other drugs that can interact with barium sulfate. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Readi-Cat 2 resources

• Readi-Cat 2 Side Effects (in more detail)
• Readi-Cat 2 Use in Pregnancy & Breastfeeding
• Readi-Cat 2 Support Group
• 1 Review for Readi-Cat 2 - Add your own review/rating

Compare Readi-Cat 2 with other medications

• Computed Tomography

Where can I get more information?

• Your doctor or pharmacist can provide more information about barium sulfate.

See also: Readi-Cat 2 side effects (in more detail)

Novobiocin Sodium

Novobiocin Sodium may be available in the countries listed below.

Ingredient matches for Novobiocin Sodium

Novobiocin

Novobiocin Sodium (BANM, USAN) is known as Novobiocin in the US.

International Drug Name Search

Glossary

BANM	British Approved Name (Modified)
USAN	United States Adopted Name

Click for further information on drug naming conventions and International Nonproprietary Names.

Actualene

Actualene may be available in the countries listed below.

Ingredient matches for Actualene

Cabergoline

Cabergoline is reported as an ingredient of Actualene in the following countries:

• Italy

International Drug Name Search

Etec

Etec may be available in the countries listed below.

Ingredient matches for Etec

Tocopherol, α-

Tocopherol, α- is reported as an ingredient of Etec in the following countries:

• Argentina


• Ecuador

International Drug Name Search

retapamulin topical

Generic Name: retapamulin topical (RE te PAM ue lin)

Brand Names: Altabax

What is retapamulin topical?

Retapamulin is an antibiotic that fights bacteria on the skin.

Retapamulin topical (for the skin) is used to treat an infection called impetigo (im-pe-TYE-go). Impetigo usually affects the nose, lips, or other areas of the face, but it may also affect other areas of the body.

Retapamulin may be used for purposes not listed in this medication guide.

What is the most important information I should know about retapamulin topical?

Do not use retapamulin topical to treat any skin condition that has not been checked by your doctor. Do not share this medication with another person, even if they have the same symptoms you have. Impetigo is highly contagious and spreads easily from person to person. Each member of the household should be seen by a doctor if they start to show symptoms of impetigo. Stop using retapamulin and call your doctor at once if you have severe burning, itching, redness, swelling, blistering, oozing, or other skin irritation where the medicine was applied.

What should I discuss with my health care provider before using retapamulin topical?

You should not use retapamulin topical if you are allergic to it. FDA pregnancy category B. Retapamulin topical is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether retapamulin topical passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not use this medication on a child younger than 9 months old.

How should I use retapamulin topical?

Use exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Apply a thin layer of retapamulin topical twice daily for at least 5 days, and longer if your doctor instructs you to. You may cover the treated skin areas with a bandage or clean gauze after applying the medicine.

Wash your hands after applying this medicine, or after touching your skin lesions for any other reason. The bacteria that causes impetigo can infect any skin area that comes into contact with your lesions. Do not use retapamulin topical to treat any skin condition that has not been checked by your doctor. This medication will not be effective in treating many other types of skin infections.

Do not share this medication with another person, even if they have the same symptoms you have. Each member of the household should be seen by a doctor if they start to show symptoms of impetigo.

Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Call your doctor if your symptoms do not improve after 3 to 4 days of treatment.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using retapamulin topical?

Impetigo is highly contagious and spreads easily from person to person. Avoid sharing personal items such as towels, washcloths, or razors with other people if you are infected with impetigo. Use a clean towel and washcloth each time you bathe to keep from reinfecting your own skin.

Avoid getting this medication in your eyes, nose, or mouth, or inside your vagina. If this does happen, rinse with water.

Avoid using other medications on the areas you treat with retapamulin topical unless you doctor tells you to.

Retapamulin topical side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using retapamulin and call your doctor at once if you have severe burning, itching, redness, swelling, blistering, oozing, or other skin irritation where the medicine was applied.

Less serious side effects may include:

• 
  

  mild skin irritation;

  
  


• 
  

  nausea, diarrhea;

  
  


• 
  

  headache; or

  
  


• 
  

  stuffy nose, sore throat.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Retapamulin topical Dosing Information

Usual Adult Dose for Impetigo:

A thin layer of retapamulin should be applied to the affected area (up to 100 squared centimeters of total area) twice daily for five days. A sterile bandage or gauze dressing may be used to cover the treated area.

Usual Pediatric Dose for Impetigo:

9 months or older: A thin layer of retapamulin should be applied to the affected area (total body surface area not exceeding 2%) twice daily for five days. A sterile bandage or gauze dressing may be used to cover the treated area.

What other drugs will affect retapamulin topical?

It is not likely that other drugs you take orally or inject will have an effect on topically applied retapamulin topical. But many drugs can interact with each other. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More retapamulin topical resources

• Retapamulin topical Side Effects (in more detail)
• Retapamulin topical Dosage
• Retapamulin topical Use in Pregnancy & Breastfeeding
• Retapamulin topical Drug Interactions
• Retapamulin topical Support Group
• 9 Reviews for Retapamulin - Add your own review/rating

• Altabax Prescribing Information (FDA)


• Altabax Monograph (AHFS DI)


• Altabax Advanced Consumer (Micromedex) - Includes Dosage Information


• Altabax Ointment MedFacts Consumer Leaflet (Wolters Kluwer)


• Altabax Consumer Overview

Compare retapamulin topical with other medications

• Acne
• Impetigo

Where can I get more information?

• Your pharmacist can provide more information about retapamulin topical.

See also: retapamulin side effects (in more detail)

Tetramisole Hydrochloride

Tetramisole Hydrochloride may be available in the countries listed below.

Ingredient matches for Tetramisole Hydrochloride

Tetramisole

Tetramisole Hydrochloride (BANM, USAN) is also known as Tetramisole (Rec.INN)

International Drug Name Search

Glossary

BANM	British Approved Name (Modified)
Rec.INN	Recommended International Nonproprietary Name (World Health Organization)
USAN	United States Adopted Name

Click for further information on drug naming conventions and International Nonproprietary Names.

Edecrin

In the US, Edecrin (ethacrynic acid systemic) is a member of the drug class loop diuretics and is used to treat Ascites, Edema, Nonobstructive Oliguria, Pulmonary Edema and Renal Failure.

US matches:

• Edecrin


• Edecrin Sodium

Ingredient matches for Edecrin

Etacrynic Acid

Etacrynic Acid is reported as an ingredient of Edecrin in the following countries:

• Australia


• Canada


• Ethiopia


• Ireland


• United States

International Drug Name Search

Timoleate

Timoleate may be available in the countries listed below.

Ingredient matches for Timoleate

Timolol

Timolol maleate (a derivative of Timolol) is reported as an ingredient of Timoleate in the following countries:

• Japan

International Drug Name Search

Urbanil

Urbanil may be available in the countries listed below.

Ingredient matches for Urbanil

Clobazam

Clobazam is reported as an ingredient of Urbanil in the following countries:

• Brazil


• Portugal

International Drug Name Search

Topraz

Topraz may be available in the countries listed below.

Ingredient matches for Topraz

Pantoprazole

Pantoprazole is reported as an ingredient of Topraz in the following countries:

• India

International Drug Name Search

Erazaban

Erazaban may be available in the countries listed below.

Ingredient matches for Erazaban

Docosanol

Docosanol is reported as an ingredient of Erazaban in the following countries:

• Latvia


• Slovakia


• Slovenia

International Drug Name Search

Torasemid AbZ

Torasemid AbZ may be available in the countries listed below.

Ingredient matches for Torasemid AbZ

Torasemide

Torasemide is reported as an ingredient of Torasemid AbZ in the following countries:

• Germany

International Drug Name Search

Etox

Etox may be available in the countries listed below.

Ingredient matches for Etox

Tocopherol, α-

Tocopherol, α- is reported as an ingredient of Etox in the following countries:

• Sri Lanka

International Drug Name Search

Pulin

Pulin may be available in the countries listed below.

Ingredient matches for Pulin

Metoclopramide

Metoclopramide hydrochloride (a derivative of Metoclopramide) is reported as an ingredient of Pulin in the following countries:

• Singapore

International Drug Name Search

Ovace

Generic Name: sulfacetamide sodium topical (SUL fa SEET a mide SOE dee um TOP i kal)

Brand Names: Klaron, Mexar, Ovace, Ovace Plus, RE 10, Seb-Prev, Sebizon

What is Ovace (sulfacetamide sodium topical)?

Sulfacetamide sodium is an antibiotic that fights bacteria on the skin.

Sulfacetamide sodium topical (for the skin) is used to treat acne, dandruff, seborrheic dermatitis (red, flaking skin rash), and certain skin infections.

Sulfacetamide sodium topical may also be used for purposes not listed in this medication guide.

What is the most important information I should know about Ovace (sulfacetamide sodium topical)?

You should not use this medication if you are allergic to sulfacetamide sodium or sulfa drugs.

Before using this medication, tell your doctor if you have asthma or a sulfite allergy, or if you are also using silver sulfadiazine (Silvadene, Thermazene).

Do not use sulfacetamide sodium topical over large skin areas.

Stop using this medication and call your doctor if your symptoms do not improve or if they get worse during treatment.

Avoid getting this medication in your nose, mouth, or eyes. Stop using sulfacetamide sodium topical and call your doctor at once if you have any type of skin rash (mild or severe), joint pain or swelling, fever or sore throat, mouth sores, pale skin, easy bruising or bleeding, unusual weakness, a new or worsening infection, or stomach pain with loss of appetite, dark urine, clay-colored stools, and jaundice (yellowing of the skin or eyes).

What should I discuss with my healthcare provider before using Ovace (sulfacetamide sodium topical)?

You should not use this medication if you are allergic to sulfacetamide sodium or sulfa drugs.

To make sure you can safely use sulfacetamide sodium topical, tell your doctor if you have asthma or a sulfite allergy.

FDA pregnancy category C. It is not known whether sulfacetamide sodium topical will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether sulfacetamide sodium topical passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not use this medication on a child younger than 12 years old.

How should I use Ovace (sulfacetamide sodium topical)?

Use exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Make sure the treatment area is clean and dry before using sulfacetamide sodium topical cream, gel, lotion, or solution. Apply the medication in a thin layer and rub in gently.

You may need to shake the medication before each use. Follow the directions on your medicine label.

To use sulfacetamide sodium soap, wet the skin and apply enough of the medication to work into a lather. Massage the lather on the skin gently and then rinse thoroughly with plain water. Pat the skin dry with a clean towel.

Do not apply sulfacetamide sodium topical over large skin areas. Wash your hands after applying this medication.

If you are using this medication on your scalp, wash your hair with a non-medicated shampoo at least once per week during treatment.

Sulfacetamide sodium topical is usually applied 2 times per day for 8 to 10 days. Space your doses evenly by applying the medication at the same times each day.

You may need to keep using the medication once or twice per week, or once every other week. Follow your doctor's instructions. Call your doctor if your condition comes back after you stop using sulfacetamide sodium topical.

Stop using this medication and call your doctor if your symptoms do not improve or if they get worse during treatment.

Store at room temperature away from moisture and heat. Do not freeze.

What happens if I miss a dose?

Apply the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include nausea and vomiting, blood in your urine, or urinating less than usual.

What should I avoid while using Ovace (sulfacetamide sodium topical)?

Do not use this medication for any skin infection that has not been checked by a doctor. Avoid getting this medication in your eyes, nose, or mouth. If this does happen, rinse with water. Do not use the medication on sunburned, windburned, dry, chapped, irritated, or broken skin. Avoid getting sulfacetamide sodium topical soap on your eyelids or lips while washing with it.

Avoid getting this medication on your clothing. Sulfacetamide sodium topical may leave a slight yellow color on light fabrics.

Avoid exposure to sunlight or tanning beds. Sulfacetamide sodium topical can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

Avoid using other medications on the areas you treat with sulfacetamide sodium topical unless you doctor tells you to.

Ovace (sulfacetamide sodium topical) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have a serious side effect such as:

• 
  

  fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;

  
  


• 
  

  patchy skin color, red spots, a butterfly-shaped skin rash over your cheeks and nose;

  
  


• 
  

  the first sign of any skin rash, no matter how mild;

  
  


• 
  

  joint pain, swelling, or stiffness;

  
  


• 
  

  signs of infection such as fever, sore throat, mouth sores, unusual weakness;

  
  


• 
  

  pale skin, easy bruising or bleeding;

  
  


• 
  

  new or worsening skin infection; or

  
  


• 
  

  nausea, pain in your upper stomach, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

  
  

Less serious side effects may include:

• 
  

  mild swelling, itching, or redness of treated skin;

  
  


• 
  

  dry skin; or

  
  


• 
  

  yellow discoloration of treated skin (may be a sign that you have applied too much of the medication).

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Ovace (sulfacetamide sodium topical)?

Tell your doctor about all other medications you use, especially silver sulfadiazine (Silvadene, Thermazene, and others).

This list is not complete and other drugs may interact with sulfacetamide sodium topical. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Ovace resources

• Ovace Side Effects (in more detail)
• Ovace Use in Pregnancy & Breastfeeding
• Ovace Support Group
• 0 Reviews for Ovace - Add your own review/rating

• Ovace Cream MedFacts Consumer Leaflet (Wolters Kluwer)


• Klaron Prescribing Information (FDA)


• Klaron Suspension MedFacts Consumer Leaflet (Wolters Kluwer)


• Mexar Wash MedFacts Consumer Leaflet (Wolters Kluwer)


• Ovace Plus Shampoo MedFacts Consumer Leaflet (Wolters Kluwer)


• Seb-Prev Prescribing Information (FDA)


• Seb-Prev Lotion MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Ovace with other medications

• Seborrheic Dermatitis
• Secondary Cutaneous Bacterial Infections

Where can I get more information?

• Your pharmacist can provide more information about sulfacetamide sodium topical.

See also: Ovace side effects (in more detail)

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