Topril

Topril may be available in the countries listed below.

Ingredient matches for Topril

Captopril

Captopril is reported as an ingredient of Topril in the following countries:

• Bangladesh

International Drug Name Search

Diconpin

Diconpin may be available in the countries listed below.

Ingredient matches for Diconpin

Isosorbide Dinitrate

Isosorbide Dinitrate is reported as an ingredient of Diconpin in the following countries:

• Germany

International Drug Name Search

Metopress

Metopress may be available in the countries listed below.

Ingredient matches for Metopress

Metoprolol

Metoprolol tartrate (a derivative of Metoprolol) is reported as an ingredient of Metopress in the following countries:

• Switzerland

International Drug Name Search

darifenacin

Generic Name: darifenacin (dar e FEN a sin)

Brand Names: Enablex

What is darifenacin?

Darifenacin reduces muscle spasms of the bladder and urinary tract.

Darifenacin is used to treat symptoms of overactive bladder, such as frequent or urgent urination, and incontinence (urine leakage).

Darifenacin may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about darifenacin?

You should not use this medication if you are allergic to darifenacin, or if you have untreated or uncontrolled narrow-angle glaucoma, a blockage in your digestive tract (stomach or intestines), or if you are unable to urinate.

Before using darifenacin, tell your doctor if you have glaucoma, liver disease, a muscle disorder, ulcerative colitis, or a blockage in your stomach or intestines.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Darifenacin can decrease perspiration and you may be more prone to heat stroke.

Darifenacin can cause side effects that may impair your vision or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly. There are many other medicines that can interact with darifenacin. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

Stop using this medication and call your doctor if you have serious side effects such as hot and dry skin, extreme thirst, severe stomach pain or constipation, pain or burning when you urinate, or if you stop urinating.

What should I discuss with my health care provider before taking darifenacin?

You should not use this medication if you are allergic to darifenacin, or have certain conditions. Be sure your doctor knows if you have:

• 
  

  untreated or uncontrolled narrow-angle glaucoma;

  
  


• 
  

  a stomach disorder causing delayed emptying; or

  
  


• 
  

  if you are unable to urinate.

  
  

Before using darifenacin, tell your doctor if you are allergic to any drugs, or if you have:

• 
  

  glaucoma;

  
  


• 
  

  liver disease;

  
  


• 
  

  ulcerative colitis;

  
  


• 
  

  a blockage in your stomach or intestines; or

  
  


• 
  

  a muscle disorder such as myasthenia gravis.

  
  

If you have any of these conditions, you may need a dose adjustment or special tests to safely take darifenacin.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether darifenacin passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take darifenacin?

Take this medication exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Take this medicine with water.

Darifenacin can be taken with or without food.

Store darifenacin at room temperature away from moisture, heat, and light.

See also: Darifenacin dosage (in more detail)

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include severe constipation or stomach pain, extreme weakness, or urinating less than usual or not at all.

What should I avoid while taking darifenacin?

Avoid becoming overheated or dehydrated during exercise and in hot weather. Darifenacin can decrease perspiration and you may be more prone to heat stroke.

Darifenacin can cause side effects that may impair your vision or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

Darifenacin side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using darifenacin and call your doctor at once if you have any of these serious side effects:

• 
  

  hot, dry skin and extreme thirst;

  
  


• 
  

  severe stomach pain or constipation;

  
  


• 
  

  pain or burning when you urinate; or

  
  


• 
  

  urinating less than usual or not at all.

  
  

Less serious side effects may include:

• 
  

  dry mouth;

  
  


• 
  

  dry eyes, blurred vision;

  
  


• 
  

  mild constipation;

  
  


• 
  

  diarrhea;

  
  


• 
  

  nausea, mild stomach pain or upset;

  
  


• 
  

  dizziness, weakness;

  
  


• 
  

  headache; or

  
  


• 
  

  fever, sore throat, body aches, or other flu symptoms.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Darifenacin Dosing Information

Usual Adult Dose for Urinary Incontinence:

Initial dose: 7.5 mg orally once daily with liquid

The dosage may be increased to 15 mg orally once daily two weeks after starting therapy.

Usual Adult Dose for Urinary Frequency:

Initial dose: 7.5 mg orally once daily with liquid

The dosage may be increased to 15 mg orally once daily two weeks after starting therapy.

What other drugs will affect darifenacin?

The following drugs can interact with darifenacin. Tell your doctor if you are using any of these:

• 
  

  other bladder or urinary medications such as flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare); or

  
  


• 
  

  glycopyrrolate (Robinul);

  
  


• 
  

  flecainide (Tambocor);

  
  


• 
  

  mepenzolate (Cantil);

  
  


• 
  

  thioridazine (Mellaril);

  
  


• 
  

  HIV /AIDS medicine such as nelfinavir (Viracept) or ritonavir (Norvir);

  
  


• 
  

  an antibiotic such as clarithromycin (Biaxin), erythromycin (E.E.S., E-Mycin, Ery-Tab, Erythrocin), or troleandomycin (Tao);

  
  


• 
  

  an antifungal medication such as itraconazole (Sporanox) or ketoconazole (Nizoral);

  
  


• 
  

  atropine (Donnatal, and others), benztropine (Cogentin), dimenhydrinate (Dramamine), methscopolamine (Pamine), or scopolamine (Transderm-Scop);

  
  


• 
  

  bronchodilators such as ipratroprium (Atrovent) or tiotropium (Spiriva);

  
  


• 
  

  irritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Anaspaz, Cystospaz, Levsin, and others), or propantheline (Pro-Banthine); or

  
  


• 
  

  an antidepressant such as amitriptyline (Elavil, Etrafon), fluoxetine (Prozac), fluvoxamine (Luvox), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), imipramine (Janimine, Tofranil), nortriptyline (Pamelor), paroxetine (Paxil), and others.

  
  

This list is not complete and there may be other drugs that can interact with darifenacin. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

More darifenacin resources

• Darifenacin Side Effects (in more detail)
• Darifenacin Dosage
• Darifenacin Use in Pregnancy & Breastfeeding
• Darifenacin Drug Interactions
• Darifenacin Support Group
• 12 Reviews for Darifenacin - Add your own review/rating

• darifenacin Advanced Consumer (Micromedex) - Includes Dosage Information


• Darifenacin Professional Patient Advice (Wolters Kluwer)


• Darifenacin Extended-Release Tablets MedFacts Consumer Leaflet (Wolters Kluwer)


• Darifenacin Hydrobromide Monograph (AHFS DI)


• Enablex Prescribing Information (FDA)


• Enablex Consumer Overview

Compare darifenacin with other medications

• Overactive Bladder
• Urinary Incontinence

Where can I get more information?

• Your pharmacist can provide more information about darifenacin.

See also: darifenacin side effects (in more detail)

Adrenalina Apolo

Adrenalina Apolo may be available in the countries listed below.

Ingredient matches for Adrenalina Apolo

Epinephrine

Epinephrine hydrochloride (a derivative of Epinephrine) is reported as an ingredient of Adrenalina Apolo in the following countries:

• Argentina

International Drug Name Search

Dentonibsa

Dentonibsa may be available in the countries listed below.

Ingredient matches for Dentonibsa

Paracetamol

Paracetamol is reported as an ingredient of Dentonibsa in the following countries:

• Portugal

International Drug Name Search

Cenipres

Cenipres may be available in the countries listed below.

Ingredient matches for Cenipres

Enalapril

Enalapril maleate (a derivative of Enalapril) is reported as an ingredient of Cenipres in the following countries:

• Austria

Nitrendipine

Nitrendipine is reported as an ingredient of Cenipres in the following countries:

• Austria

International Drug Name Search